Overview of facilities
| Name of equipment/device | Manufacturer | Note |
|---|---|---|
| Handling of highly active pharmacological equipment |
OEL:0.1 - 1µg/m3 | |
| HPLC | Shimadzu Corporation, Hitachi, Ltd. |
Multiple units |
| GC | Shimadzu Corporation | Multiple units |
| FT-NMR | JEOL Ltd. | 400MHz (4 units) |
| GC-MS | Shimadzu Corporation | GCMS-QP2010plus |
| GC-MS | Shimadzu Corporation | GCMS-QP2020NX |
| LC-MS (Quadrupole) | Waters, Shimadzu Corporation |
Can accommodate UPLC (Waters Corporation), APCI (Shimadzu Corporation) |
| MALDI-TOF-MS | Shimadzu Corporation | AXIMA |
| GPC separation system | Japan Analytical Industry Co., Ltd | LC-908, LC-9130NEXT |
| HPLC fractionation system | GL Sciences, Inc., Shimadzu Corporation |
|
| MPLC (medium pressure chromatography) system |
Moritex, Ltd, Yamazen Corporation |
|
| Infrared spectrophotometer (FT-IR) | Thermo | iS10 |
| Ultraviolet spectrophotometer (UV) | Shimadzu Corporation | UV-1800, etc. |
| Spectrophotometer | DeNovix, Inc. | DS-11+ |
| ICP-OES | Agilent Technologies, Inc. | 710ICP-OES |
| ICP-MS | Perkin Elmer Co., Ltd | 710ICP-OES |
| Glovebox | UNICO | 6 units |
| Contact-angle tensiometer | FACE | |
| Thermal analysis device | NETSCH | DSC-3100SA |
| Thermal analysis device | Mac Science (X-ray Science Corporation) | TG-DTA200SA |
| Photoreactors | Eikosha Co., Ltd. | High- and low-pressure mercury lamps |
| Ozone generators | Sumitomo Precision Products, Ltd. | Approximately 3.5 g/hr |
| Microwave reactor | Shikoku Instrumentation Co., Ltd. | |
| Ultrasonic oscillator | SMT UH-150 | |
| High-vacuum distillation system | In-house assembly | 30+ fractions, min., ≥1 Torr |
| Sublimation equipment | In-house production | |
| Lyophilizer equipment | Tokyo Rikakikai Co., Ltd. | |
| Autoclave | Taiatsu Techno Corporation | 50 mL - 3.0 L, multiple units |
| Centrifuge separator | KUBOTA | 7000 6200 |
| Fluorescence spectrophotometer | Shimadzu Corporation | RF-6000 |
| CHN elemental analyzer | Perkin Elmer Co., Ltd. | 2400II |
| Karl Fischer moisture meter (titration method) | Kyoto Electronics Manufacturing Co., Ltd. | MKH-700, MKV-710 |
| Moisture vaporator device | Kyoto Electronics Manufacturing Co., Ltd. | ADP-611 |
| MS trigger system for measurements | Waters, Shimadzu Corporation |
|
| Polarimeter instrument | JASCO Corporation | |
| GPC analysis equipment | Tosoh Corporation, Viscotek Co., Ltd., Shimadzu Corporation |
Multiple Units |
| GPC (Optical Scatter) | Viscotech Co., Ltd. | |
| X-ray Powder Diffractometry | PANalytical | X'pert3powder |
| FE-SEM | JEOL Ltd. | TSM-7610F |
| DLS | Malvern | Zetasizer Nano ZS |
| Tensile tester | Shimadzu Corporation | AUTOGRAPH |
| Laser diffraction scattering-type particle size measuring analyzer |
Shimadzu Corporation | SALD-2300 |
| Particle-size scatter measuring apparatus | Horiba Ltd. | CAPA-700 |
| Color and shade difference meter | Konica-Minolta, Inc. | |
| Surface structure analyzer | Tokyo Seimitsu Co., Ltd. | |
| Impact tester (coating) | Taiyu Kizai. Co., Ltd. | |
| Drawing tester (coating) | Taiyu Kizai. Co., Ltd. | |
| Bending tester (coating) | Taiyu Kizai. Co., Ltd. | |
| Gloss meter | MURAKAMI COLOR | |
| Adhesion tester | Oxjack Co., Ltd. | |
| UV irradiation device | Toshiba Corporation | |
| Electrical furnace | Ikeda Chemical Co., Ltd, As One Corporation, etc. |
- 1500℃ |
| Homomixer | Primix Corporation | |
| Homogenizer | Nissei Corporation | |
| Ultrasonic homogenizer | SONICS | VCX-500 |
| Planetary ball-mill | Fritsch Japan Co.,Ltd. | P-7, premium line P-7 |
| SC-type grinding mill | Nippon Coke & Engineering Co., Ltd. | SC-16 |
| Spin-coating machine | Mikasa Industrial Products Co., Ltd. | |
| Non-bubbling kneader | Nissei Corporation | NBK-1 |
| Tabletop kneader | Irie Shokai Co, Ltd. | PNV-1H type |
| Microscope | Keyence Corporation | VHX-900 |
| Deaerator | Thinky Corporation | Awatori Rentaro ARV-310 |
| Surface meter | Quantachrome Corporation | Monosorb |
| Dip coater | Asumi Giken, Ltd. | N100 |
| B-type viscometer | Toki Sangyo Co., Ltd. | TVB-15 |
| E-type viscometer | Toki Sangyo Co., Ltd. | TV-22, TV-25 |
NARD Institute, Ltd (main equipment as of October 2018)
Process flow management department 
Technical department 
Quality control department
Reaction equipment (d2G4 applicable)
| Reactor (SUS) | Reactor (GL) |
|---|---|
|
|
NARD Chemicals, Ltd (main equipment as of December 2018)
Cleanroom number one (Class 10,000)
| Water purification equipment x1 | Filter (GL) | Jet pulverizer |
| GL 200 L reactor x1 | GL 100 L reactor x1 | SUS vacuum tray dryer (3m2) |
NARD Chemicals, Ltd (main equipment as of December 2018)
Cleanroom number one 
500 L GL reactor
(Pressure resistance: 0.5 MPa)
500 L SUS reactor
(Pressure resistance: 0.88 MPa)
Cleanroom number two (Class 100,000)
| 16m2 Small-scale production and purification equipment |
NARD Chemicals, Ltd (main equipment as of December 2018)
Auxiliary equipment
| Centrifugal-flow thin-film vacuum evaporator | (Capacity: 200 kg/h) x1 |
|---|---|
| Portable agitator | 8 |
| Oil heater/cooler | MAX250℃x30kw |
| Steam boiler | (500kg/h)x2 |
| Freezer (－20℃, brine) | 90,000kcal/h, 69,000kcal/h, 50,000kcal/ｈ |
| Filtration equipment | 30 inch centrifuge: (SUS)x2, (resin-lined) x1 30 inch centrifuge: Portable aflon-lined x1 PP filter press (3.3m2)x2, (1.0m2)x1, (7.2m2)x1 Pressure filtration equipment, (SUS) x2, (GL) x2 Nutsche vacuum filtration machine, (SUS) x13, (PP) x8 |
| Vacuum pump | (oil-sealed rotary) x 9, (water-sealed) x6, mechanical booster x7 |
| Dryer | Vacuum dryer (GL: conical), 500 L volume x1 Vacuum dryer (SUS: shelved), 1.8m2 - 5m2 cubic volume x6 Vacuum dryer (SUS: conical), 700 L volume x1, 100 L x1 Vacuum dryer (SUS: shelved), 1,300 L volume x1 |
| Cryogenic freezer | -25℃ 310Lx1, 500Lx1, -35℃ 360Lx5, 420Lx1, -60℃ 470Lx2, -80℃ 180Lx1 |
| Cooling box | 16.5m2x1 |
| Rotary evaporator | 10Lx1, 100Lx4 |
| Chromatography column | (PYREX)100Lx1 (SUS)50Lx1, 100Lx2, 200Lx2 260 L short column x1, 200 L short column x1 |
| Ion exchange water system | 2 |
| Grinder mill | Sample mill x1, cutter mill x1 |
NARD Chemicals, Ltd (main equipment as of December 2018)
400 L SUS reactor 
100 L Rotary evaporator 
Centrifugal-flow thin-film vacuum evaporator 
Vacuum dryer (SUS shelved) 
Vacuum dryer (SUS conical) 
Filter press
Main analytical equipment
| Gas chromatograph (FID) | Liquid chromatography (UV, PDA, RI, GPC) | Karl Fischer moisture meter (volumetric method, coulometric method) |
| Infrared spectrophotometer | Spectrophotometer | Polarimeter |
| Automatic titrator | Particle-size-scatter measuring apparatus | Thermo-hygrostat |
| Liquid chromatography mass analyzer (LC/MS) | Photostability testing apparatus |
NARD Chemicals, Ltd (main equipment as of December 2018)
Related contents
Inquiries about Facilities and Manufacturing plants
Please contact us for consultations or inquiries.
