NARD Institute facilities overview
Name of equipment/device | Manufacturer | Note |
---|---|---|
Handling of highly active pharmacological equipment |
OEL:0.1 - 1µg/m3 | |
HPLC | Shimadzu Corporation, Hitachi, Ltd. |
Multiple units |
GC | Shimadzu Corporation | Multiple units |
FT-NMR | JEOL Ltd. | 400MHz (4 units) |
GC-MS | Shimadzu Corporation | GCMS-QP2010plus |
GC-MS | Shimadzu Corporation | GCMS-QP2020NX |
LC-MS (Quadrupole) | Waters, Shimadzu Corporation |
Can accommodate UPLC (Waters Corporation), APCI (Shimadzu Corporation) |
MALDI-TOF-MS | Shimadzu Corporation | AXIMA |
GPC separation system | Japan Analytical Industry Co., Ltd | LC-908, LC-9130NEXT |
HPLC fractionation system | GL Sciences, Inc., Shimadzu Corporation |
|
MPLC (medium pressure chromatography) system |
Moritex, Ltd, Yamazen Corporation |
|
Infrared spectrophotometer (FT-IR) | Thermo | iS10 |
Ultraviolet spectrophotometer (UV) | Shimadzu Corporation | UV-1800, etc. |
Spectrophotometer | DeNovix, Inc. | DS-11+ |
ICP-OES | Agilent Technologies, Inc. | 710ICP-OES |
ICP-MS | Perkin Elmer Co., Ltd | 710ICP-OES |
Glovebox | UNICO | 6 units |
Contact-angle tensiometer | FACE | |
Thermal analysis device | NETSCH | DSC-3100SA |
Thermal analysis device | Mac Science (X-ray Science Corporation) | TG-DTA200SA |
Photoreactors | Eikosha Co., Ltd. | High- and low-pressure mercury lamps |
Ozone generators | Sumitomo Precision Products, Ltd. | Approximately 3.5 g/hr |
Microwave reactor | Shikoku Instrumentation Co., Ltd. | |
Ultrasonic oscillator | SMT UH-150 | |
High-vacuum distillation system | In-house assembly | 30+ fractions, min., ≥1 Torr |
Sublimation equipment | In-house production | |
Lyophilizer equipment | Tokyo Rikakikai Co., Ltd. | |
Autoclave | Taiatsu Techno Corporation | 50 mL - 3.0 L, multiple units |
Centrifuge separator | KUBOTA | 7000 6200 |
Fluorescence spectrophotometer | Shimadzu Corporation | RF-6000 |
CHN elemental analyzer | Perkin Elmer Co., Ltd. | 2400II |
Karl Fischer moisture meter (titration method) | Kyoto Electronics Manufacturing Co., Ltd. | MKH-700, MKV-710 |
Moisture vaporator device | Kyoto Electronics Manufacturing Co., Ltd. | ADP-611 |
MS trigger system for measurements | Waters, Shimadzu Corporation |
|
Polarimeter instrument | JASCO Corporation | |
GPC analysis equipment | Tosoh Corporation, Viscotek Co., Ltd., Shimadzu Corporation |
Multiple Units |
GPC (Optical Scatter) | Viscotech Co., Ltd. | |
X-ray Powder Diffractometry | PANalytical | X'pert3powder |
FE-SEM | JEOL Ltd. | TSM-7610F |
DLS | Malvern | Zetasizer Nano ZS |
Tensile tester | Shimadzu Corporation | AUTOGRAPH |
Laser diffraction scattering-type particle size measuring analyzer |
Shimadzu Corporation | SALD-2300 |
Particle-size scatter measuring apparatus | Horiba Ltd. | CAPA-700 |
Color and shade difference meter | Konica-Minolta, Inc. | |
Surface structure analyzer | Tokyo Seimitsu Co., Ltd. | |
Impact tester (coating) | Taiyu Kizai. Co., Ltd. | |
Drawing tester (coating) | Taiyu Kizai. Co., Ltd. | |
Bending tester (coating) | Taiyu Kizai. Co., Ltd. | |
Gloss meter | MURAKAMI COLOR | |
Adhesion tester | Oxjack Co., Ltd. | |
UV irradiation device | Toshiba Corporation | |
Electrical furnace | Ikeda Chemical Co., Ltd, As One Corporation, etc. |
- 1500℃ |
Homomixer | Primix Corporation | |
Homogenizer | Nissei Corporation | |
Ultrasonic homogenizer | SONICS | VCX-500 |
Planetary ball-mill | Fritsch Japan Co.,Ltd. | P-7, premium line P-7 |
SC-type grinding mill | Nippon Coke & Engineering Co., Ltd. | SC-16 |
Spin-coating machine | Mikasa Industrial Products Co., Ltd. | |
Non-bubbling kneader | Nissei Corporation | NBK-1 |
Tabletop kneader | Irie Shokai Co, Ltd. | PNV-1H type |
Microscope | Keyence Corporation | VHX-900 |
Deaerator | Thinky Corporation | Awatori Rentaro ARV-310 |
Surface meter | Quantachrome Corporation | Monosorb |
Dip coater | Asumi Giken, Ltd. | N100 |
B-type viscometer | Toki Sangyo Co., Ltd. | TVB-15 |
E-type viscometer | Toki Sangyo Co., Ltd. | TV-22, TV-25 |
NARD Institute, Ltd (main equipment as of October 2018)
NARD Chemicals facilities overview
Reaction equipment (d2G4 applicable)
Reactor (SUS) | Reactor (GL) |
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|
|
NARD Chemicals, Ltd (main equipment as of January 2024)
Cleanroom number one (Class 10,000)
Water purification equipment x1 | Filter (GL) | Jet pulverizer |
GL 200 L reactor x1 | GL 100 L reactor x1 | SUS vacuum tray dryer (3m2) |
NARD Chemicals, Ltd (main equipment as of December 2018)
Cleanroom number one 500 L GL reactor
(Pressure resistance: 0.5 MPa)500 L SUS reactor
(Pressure resistance: 0.88 MPa)
Cleanroom number two (Class 100,000)
16m2 Small-scale production and purification equipment |
NARD Chemicals, Ltd (main equipment as of December 2018)
Auxiliary equipment
Centrifugal-flow thin-film vacuum evaporator | (Capacity: 200 kg/h) x1 |
---|---|
Portable agitator | 8 |
Oil heater/cooler | MAX250℃x30kw |
Steam boiler | (500kg/h)x2 |
Freezer (-20℃, brine) | 90,000kcal/h, 69,000kcal/h, 50,000kcal/h |
Filtration equipment | 30 inch centrifuge: (SUS)x2, (resin-lined) x1 30 inch centrifuge: Portable aflon-lined x1 PP filter press (3.3m2)x2, (1.0m2)x1, (7.2m2)x1 Pressure filtration equipment, (SUS) x2, (GL) x2 Nutsche vacuum filtration machine, (SUS) x13, (PP) x8 |
Vacuum pump | (oil-sealed rotary) x 9, (water-sealed) x6, mechanical booster x7 |
Dryer | Vacuum dryer (GL: conical), 500 L volume x1 Vacuum dryer (SUS: shelved), 1.8m2 - 5m2 cubic volume x6 Vacuum dryer (SUS: conical), 700 L volume x1, 100 L x1 Vacuum dryer (SUS: shelved), 1,300 L volume x1 |
Cryogenic freezer | -25℃ 310Lx1, 500Lx1, -35℃ 360Lx5, 420Lx1, -60℃ 470Lx2, -80℃ 180Lx1 |
Cooling box | 16.5m2x1 |
Rotary evaporator | 10Lx1, 100Lx4 |
Chromatography column | (PYREX)100Lx1 (SUS)50Lx1, 100Lx2, 200Lx2 260 L short column x1, 200 L short column x1 |
Ion exchange water system | 2 |
Grinder mill | Sample mill x1, cutter mill x1 |
NARD Chemicals, Ltd (main equipment as of December 2018)
400 L SUS reactor 100 L Rotary evaporator Centrifugal-flow thin-film vacuum evaporator Vacuum dryer (SUS shelved) Vacuum dryer (SUS conical) Filter press
Main analytical equipment
Gas chromatograph (FID) | Liquid chromatography (UV, PDA, RI, GPC) | Karl Fischer moisture meter (volumetric method, coulometric method) |
Infrared spectrophotometer | Spectrophotometer | Polarimeter |
Automatic titrator | Particle-size-scatter measuring apparatus | Thermo-hygrostat |
Liquid chromatography mass analyzer (LC/MS) | Photostability testing apparatus |
NARD Chemicals, Ltd (main equipment as of December 2018)
Process flow management department Technical department Quality control department
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