Serotonin

Order number	PP025-0
Name	DASB
Chemical Formula	C16H17N3S
Molecular Weight	283.39
Purity	> 95%
Packaging	min. 10 mg, or as ordered
Purpose	Reference standard for [11C]DASB
Other name	N,N-Dimethyl-2-(2-amino-4-cyanophenylthio)benzylamine; 3-Amino-4-(2-dimethylaminomethylphenylsulfanyl)benzonitrile
CA index name	Benzonitrile, 3-amino-4-[[2-[(dimethylamino)methyl]phenyl]thio]-
Literature	1. Houle S, Ginovart N, Hussey D, Meyer JH, Wilson AA. Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB. Eur J Nucl Med. 2000;27(11):1719-22. 2. Wilson AA, Ginovart N, Schmidt M, Meyer JH, Threlkeld PG, Houle S. Novel radiotracers for imaging the serotonin transporter by positron emission tomography: synthesis, radiosynthesis, and in vitro and ex vivo evaluation of 11C-labeled 2-(phenylthio)araalkylamines.J Med Chem. 2000;43(16):3103-10. 3. Takano A, Suzuki K, Kosaka J, Ota M, Nozaki S, Ikoma Y, Tanada S, Suhara T. A dose-finding study of duloxetine based on serotonin transporter occupancy. Psychopharmacology (Berl). 2006;185(3):395-9.
	serotonin transporter