Translocator protein (TSPO)
| Order number | PP010-0 |
|---|---|
| Name | (R) –PK11195 |
| Chemical Formula | C21H21ClN2O |
| Molecular Weight | 352.86 |
| Purity | > 95% |
| Packaging | min. 10 mg, or as ordered |
| Purpose | Reference standard for (R)-[N-methyl-11C-]PK11195 |
| Other name | (R)-1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-isoquinoline-3-Carboxamide |
| CA index name | 3-isoquinolinecarboxamide, 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-,(R) |
| Literature | 1. Camsonne R., Crouzel C., Comar D., Mazière M, Prenant C, Sastre J, Moulin M, Syrota A. Synthesis of N -(11C) methyl, N -(methyl-1 propyl), (chloro-2 phenyl)-1 isoquinoleine carboxamide-3 (PK 11195): A new ligand for peripheral benzodiazepine receptors. J. Label. Compd. Radiopharm. 1984;21:985-991. 2. Shah F, Hume SP, Pike VW, Ashworth S, McDermott J. Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats. Nucl Med Biol. 1994; 21(4):573-581. 3. Charbonneau P, Syrota A, Crouzel C, Valois JM, Prenant C, Crouzel M. Peripheral-type benzodiazepine receptors in the living heart characterized by positron emission tomography. Circulation. 1986; 73(3):476-483. |
| 18 kDa-translocator protein (TSPO) |
