Dopamine

Order number PP008-0
Name Fallypride
Chemical Formula C20H29FN2O3
Molecular Weight 364.45
Purity > 95%
Packaging min. 10 mg, or as ordered
Purpose Reference standard for [18F]Fallypride
Other name  
CA index name Benzamide,5-(3-fluoropropyl)-2,3-dimethoxy-N-[[(2S)-1-(2-propenyl)-2-pyrrolidinyl]methyl]-
Literature 1. Mukherjee J., Yang Z.Y., Das M.K., Brown T. Fluorinated benzamide neuroleptics--III. Development of (S)-N-[(1-allyl-2-pyrrolidinyl)methyl]-5-(3-[18F]fluoropropyl)-2,3-dimethoxybenzamide as an improved dopamine D2 receptor tracer. Nucl Med Biol. 1995;22(3):283-96.
2. Gründer G, Landvogt C, Vernaleken I, Buchholz HG, Ondracek J, Siessmeier T, Härtter S, Schreckenberger M, Stoeter P, Hiemke C, Rösch F, Wong DF, Bartenstein P. The striatal and extrastriatal D 2/D3 receptor-binding profile of clozapine in patients with schizophrenia. Neuropsychopharmacology 2006;31(5):1027-35.
3. Mukherjee J., Christian B.T., Narayanan T.K., Shi B., Collins D.. Measurement of d-amphetamine-induced effects on the binding of dopamine D 2/D3 receptor radioligand, 18F-fallypride in extrastriatal brain regions in non-human primates using PET. Brain Res. 2005;1032(1-2) :77-84.
  D2 receptor