Dopamine
| Order number | PP004-0 |
|---|---|
| Name | (R)-(+)-SCH-23390 |
| Chemical Formula | C17H18ClNO (Free base) |
| Molecular Weight | 287.78 (Free base) |
| Purity | > 95% |
| Packaging | min. 10 mg, or as ordered |
| Purpose | Reference standard for [11C]SCH-23390 |
| Other name | N-(t-Butoxycarbonyl)-3,4-di(t-butoxycarbonyloxy)-6-(trimethylstannyl)-L-phenylalanine methyl ester ; 6-Me3Sn-triBoc-L-DOPA |
| CA index name | L-Tyrosine, 5[[(1,1-dimethylethoxy)carbonyl]oxy]-N-[(1,1-dimethylethoxy) carbonyl]-2-(trimethylstannyl)-, methyl ester, 1,1-dimethylethyl carbonate |
| Literature | 1. Halldin C, Stone-Elander S, Farde L, Ehrin E, Fasth KJ, Långström B, Sedvall G. Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D1 receptors using positron emission tomography.Int. J. Appl. Radiat. Isot. 1986;37, 1039-1043. 2. Farde L, Halldin C, Stone-Elander S, Sedvall G. PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride. Psychopharmacoligy 1987;92:278-284. 3. Okubo Y, Suhara T, Suzuki K, Kobayashi K, Inoue O, Terasaki O, Someya Y, Sassa T, Sudo Y, Matsushima E, Iyo M, Tateno Y, Toru M. Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET. Nature 1997;385: 634-636. |
| Dopamine D1 receptor antagonist Free base or hydrochloride salt or maleate |
