Translocator protein (TSPO)
| Order number | NP067-0 |
|---|---|
| Name | AC-5216 |
| Chemical Formula | C23H23N5O2 |
| Molecular Weight | 401.47 |
| Purity | > 95% |
| Packaging | min. 10 mg, or as ordered |
| Purpose | Reference standard for [11C]AC-5216 |
| Other name | N-benzyl-N-ethyl-2-(7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-yl)acetamide; N-benzyl-N-ethyl-2-(7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ; Emapunil |
| CA index name | |
| Literature | 1. Zhang M.R., Kumata K., Maeda J., Yanamoto K., Hatori A., Okada M., Higuchi M., Obayashi S., Suhara T., Suzuki K. 11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain. J. Nucl. Med. 2007; 48(11):1853-61. 2. Yanamoto K., Zhang M.R., Kumata K., Hatori A., Okada M., Suzuki K. In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats. Neurosci Lett. 2007; 428(2-3):59-63. 3. Amitani M., Zhang M.R., Noguchi J., Kumata K., Ito T., Takai N., Suzuki K., Hosoi R., Inoue O. Blood flow dependence of the intratumoral distribution of peripheral benzodiazepine receptor binding in intact mouse fibrosarcoma. Nucl. Med. Biol. 2006; 33(8):971-5. |
| 18 kDa-translocator protein (TSPO) |
