Translocator protein (TSPO)

Order number NP066-0
Name FEDAA1106
Chemical Formula C24H23F2NO4
Molecular Weight 427.45
Purity > 95%
Packaging min. 10 mg, or as ordered
Purpose Reference standard for [18F]FEDAA1106
Other name N-(5-fluoro-2-phenoxyphenyl)-N-(2-fluoroethyl-5-methoxybenzyl)acetamide ; FEtDAA1106
CA index name Acetamide, N-[[2-(2-fluoroethoxy)-5-methoxyphenyl]methyl]-N-(5-fluoro-2-phenoxyphenyl)-
Literature 1. Zhang M.R., Maeda J., Furutsuka K., Yoshida Y., Ogawa M., Suhara T., Suzuki K. [18F]FMDAA1106 and [18F]FEDAA1106: two positron-emitter labeled ligands for peripheral benzodiazepine receptor (PBR). Bioorg Med Chem Lett. 2003; 13(2):201-4.
2. Zhang M.R., Maeda J., Ogawa M., Noguchi J., Ito T., Yoshida Y., Okauchi T., Obayashi S., Suhara T., Suzuki K.. Development of a new radioligand, N-(5-fluoro-2-phenoxyphenyl)- N -(2-[18F]fluoroethyl-5-methoxybenzyl)acetami de, for pet imaging of peripheral benzodiazepine receptor in primate brain. J Med Chem. 2004; 47(9):2228-35.
3. Fujimura Y, Ikoma Y, Yasuno F, Suhara T, Ota M, Matsumoto R, Nozaki S, Takano A, Kosaka J, Zhang MR, Nakao R, Suzuki K, Kato N, Ito H. Quantitative Analyses of 18F-FEDAA1106 Binding to Peripheral Benzodiazepine Receptors in Living Human Brain. J Nucl Med. 2006; 47(1):43-50.
  18 kDa-translocator protein (TSPO)