NARD Institute technical keywords

Dendrimers

From synthesis of dendrimers to new dendrimer precursors, NARD Institute is the answer to your needs.

Dendrimers, or cascade molecules, are branched polymer macromolecules first reported in 1984 by D. A. Tomalia, et. al.
Dendrimers are generally monodisperse (under 10 nm) and amorphous, with low viscosity. They exhibit features not found in conventional polymers, such as core and outer shell functionality, single-molecule micelle formation, and the possibility of incorporating metals or other molecules inside. Additionally, as high-generation dendrimers may be considered molecular spheres, it is possible to introduce a large number of functional groups to the molecular surface, and so they are expected to yield new highly functional materials in chemical fields such as pharmaceuticals and electronic materials.

Dendrimers are composed of three elements: the core, the branching structure, and the outer shell (termini). While the properties of the outer shell determine reactivity and solubility, the core has an effect on size and functionality.
There are two methods for synthesis of dendrimers: divergent, which involves stepwise (generational) extension of the branches from a central molecule; and convergent, which involves synthesizing the branches completely, before finally coupling to the core molecule. Thus, compared to conventional polymer synthesis, structural control is simple, and design possibilities are diverse. From the basic precursors a variety of forms and sizes may be constructed.

Making full use of our accumulated synthetic experience in fine chemicals, NARD Institute is performing contracted research and synthesis of dendrimer precursors (building-blocks).

Also, if required, we can construct cores to support the creation of dendrimers with new functional properties.

Example: 4- & 5-generation dendrimer building-blocks

In addition, we also accept contracts for the relatively simple synthesis of custom hyper-branched polymers. While dendrimers require repeated protection-deprotection, hyperbranched polymers are generally synthesized in a one-step polymerization of ABx polymers.
Using a variety of polymerization techniques, we can provide novel hyperbranched polymers.

There are many more examples of our achievements and capabilities. Please feel free to inquire.
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